Scientific Program

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March 29 (Thursday)

Educational Session 01

Multiple Myeloma

Date & Time March 29 (Thu), 09:00-10:00 Venue Room A Language Korean
Speakers

1. Monoclonal Gammopathy of Renal Significance

Jung Eun Lee, Department of Medicine, Sungkyunkwan University School of Medicine, Samsung Medical Center, Korea

2. Smoldering Multiple Myeloma

Byung-Su Kim, Department of Hemato-Oncology, Hallym University Dongtan Sacred Heart Hospital, Korea

3. Next Generation Sequencing in Multiple Myeloma

Miyoung Kim, Department of Laboratory Medicine, Hallym University College of Medicine, Korea

Educational Session 02

Typical and atypical Chronic Myelogenous Leukemia

Date & Time March 29 (Thu),09:00-10:00 Venue Room B Language Korean
Speakers

1. Optimal First-line Treatment of Chronic Phase CML

Kyoung ha Kim, Division of Hematology-Oncology, Department of Internal Medicine, Soonchunhyang University Hospital Seoul, Korea

2. Update on the Treatment of CML in Children

Jae Wook Lee, Department of Pediatrics, College of Medicine, The Catholic University of Korea, Korea

3. BCR-ABL1 Negative Hematologic Neoplasms; Diseases that are Similar to but Different from CML

Hawk Kim, Division of Hematology, Gachon University College of Medicine, Korea

Educational Session 03

Thrombotic Microangiopathy

Date & Time March 29 (Thu), 09:00-10:00 Venue Room C Language Korean
Speakers

1. Childhood aHUS

Hae Il Cheong, Department of Pediatrics, Seoul National University College of Medicine, Korea

2. Adult aHUS

Youngil Koh, Department of Internal Medicine, Seoul National University College of Medicine, Korea

3. Management of TTP

Doyeun Oh, Department of Internal Medicine, CHA University School of Medicine, Korea

Scientific Session 01

Single Cell Genomics

Date & Time March 29 (Thu),10:20-11:40 Venue Room A Language English
Speakers

1. Single Cell Genome Analysis in Human Cancers

Woong-Yang Park, Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Korea

2. Characteristics of Tumor Infiltrating Lymphocytes Revealed by Single Cell RNA     Sequencing

Zemin Zhang, Peking University, China

3. Dissecting the Cellular and Genetic Composition of Pediatric Leukemias by Single-Cell Genomics

Charles Gawad, St. Jude Children's Research Hospital, USA

Scientific Session 02

Cancer Immunology

Date & Time March 29 (Thu),10:20-11:40 Venue Room B Language English
Speakers

1. Immune Checkpoint Inhibition in Hematologic Malignancy - Focusing on Multiple Myeloma

Yoon Seok Choi, Department of Internal Medicine, Chungnam National University College of Medicine, Korea

2. A New Antigen Presenting Cell based Therapeutic Cancer Vaccine

Chang-yuil Kang, Laboratory of Immunology, College of Pharmacy, Seoul National University, Korea

3. Chimeric Antigen Receptor-Engineered Natural Killer Cell Immunotherapy for Cancer

Kyung-Nam Koh, Department of Pediatrics, University of Ulsan College of Medicine, Korea

4. Post-transplant Immunotherapy with WT1-specific CTLs for High-risk AML

Tai-Gyu Kim, Department of Microbiology, Catholic Hematopoietic Stem Cell Bank, College of Medicine, The Catholic University of Korea, Korea

[Luncheon] Satellite Symposium 01

KYOWA KIRIN

Date & Time March 29 (Thu), 13:00-14:00 Venue Room A Language English
Speakers

1. Updated Febrile Neutropenia Management

Won Seog Kim, Samsung Medical Center, Korea

[Luncheon] Satellite Symposium 02

NOVARTIS

Date & Time March 29 (Thu), 13:00-14:00 Venue Room B Language English
Speakers

1. It's Time We Go Deeper

Pierre Laneuville, McGill University Health Centre Montreal, Canada

[Luncheon] Satellite Symposium 03

HANDOK

Date & Time March 29 (Thu), 13:00-14:00 Venue Room C Language English
Speakers

1. Complement Mediated Glomerular Disease(Focusing on aHUS): Everything Has Changed in the Last 10 Years but Still a Lot to Do

Giuseppe Remuzzi, Mario Negri Institute for Pharmacological Research, Italy

Plenary Lecture 01

Precision Hematology in Genomics Era

Date & Time March 29 (Thu), 14:00-15:20 Venue Room A~C Language English
Speakers

1. Precision Medicine in CLL

Constantine Tam, Peter MacCallum Cancer Centre, St Vincent’s Hospital and University of Melbourne, Australia

2. The Clinical Management of FLT3-Mutated AML

Mark Levis, Johns Hopkins School of Medicine, USA

KSH-EHA Joint Symposium 01

Myelodysplastic Syndrome

Date & Time March 29 (Thu),15:40-17:00 Venue Room A~B Language English
Speakers

1. The Best Prediction of Prognosis for MDS: How to Integrate Clinical and Molecular Data

Valeria Santini, University of Florence, Italy

2. Clinical Effects of Somatic Mutations in MDS

Je-Hwan Lee, Department of Hematology, University of Ulsan College of Medicine, Korea

3. Pathogenesis and Management of CMMoL

Raphael Itzykson, Department of Hematology, Paris Diderot University, France

4. Hypomethylating Therapy in Stem Cell Transplantation for MDS

Yoo-Jin Kim, Department of Hematology, College of Medicine, The Catholic University of Korea, Korea

Special Report 01

Updates on Cellular therapies

Date & Time March 29 (Thu),15:40-17:00 Venue Room C Language English
Speakers

1. CAR T Treatment for ALL

Jae Park, Memorial Sloan Kettering Cancer Center (MSKCC), USA

2. CAR Expressing Effector Cells in Stem Cell Transplantation

Ulrike Kohl, Hannover Medical School, Germany

3.Ex Vivo T cell-depleted Haploidentical Hematopoietic Cell Transplantation and Cellular Therapy Post-transplantation

Ho Joon Im, Department of Pediatrics, University of Ulsan College of Medicine, Korea

March 30 (Friday)

Scientific Session 03

Recent Advances in Acute Promyelocytic Leukemia

Date & Time March 30 (Fri), 09:00-10:20 Venue Room A Language English
Speakers

1. JALSG Prospective Study for APL

Akihiro Takeshita, Transfusion and Cell Therapy, Hamamatasu University School of Medicine, Japan

2. Therapy of APL

Lionel Ades, des Universités-Praticien Hospitalier, Service d’hématologie Sénior, France

3. Strategies to Define High-risk Patients in APL

Byung-Sik Cho, Division of Hematology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Korea

Scientific Session 04

Recent Advances in Natural Killer T-cell Lymphoma

Date & Time March 30 (Fri), 09:00-10:20 Venue Room B Language English
Speakers

1. Molecular Pathogenesis of NKTL

Wee Joo Chng, National University Cancer Institute, Singapore

2. Current Standard Treatment of ENKTL

Yok Lam Kwong, University of Hong Kong, Hong Kong

3. Beyond Current Standard Care of ENKTL

Won Seog Kim, Samsung Medical Center, Korea

Plenary Lecture 02

Targeting Leukemic Stem Cells

Date & Time March 30 (Fri), 10:30-11:50 Venue Room A~C Language English
Speakers

1. Human Myeloid Leukemia Stem Cells

Koichi Akashi, Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Japan

2. Pre-Cancerous Stem Cells in MDS and AML: Significance, Mechanisms, and Therapeutic Targeting

Ulrich Steidl, Department of Cell Biology, and Department of Medicine, Albert Einstein College of Medicine, USA

[Luncheon] Satellite Symposium 04

AMGEN

Date & Time March 30 (Fri), 12:00-13:00 Venue Room A Language English
Speakers

1. Leading towards Optimizing the Treatment Strategies of Relapsed or Refractory Multiple Myeloma

Keith Stewart, Mayo Clinic, USA

[Luncheon] Satellite Symposium 05

BMS

Date & Time March 30 (Fri), 12:00-13:00 Venue Room B Language English
Speakers

1. Emerging Trends in CML Management

Elias Jabbour, Leukemia Department, MD Anderson Cancer Center, USA

[Luncheon] Satellite Symposium 06

HANDOK

Date & Time March 30 (Fri), 12:00-13:00 Venue Room C Language English
Speakers

1. HSCT Early Complications: Focus on Severe Hepatic Veno-occlusive Disease;
- The Revised EBMT Diagnostic and Severity Criteria for Adults and an Update on Defibrotide.

Mohamad Mohty, EBMT chairperson, France

Scientific Session 05

Cell Death Mechanism

Date & Time March 30 (Fri), 13:00-14:20 Venue Room A Language English
Speakers

1. Apoptotic Cell Death

Soo Youl Kim, Cancer Microenvironment Branch, Division of Cancer Biology, National Cancer Center, Korea

2. CHIP Controls Necroptosis Through Ubiquitylation- and Lysosome-dependent Degradation of RIPK3

Jaewhan Song, Department of Biochemistry, Yonsei University, Korea

3. Autophagy

Yong-Keun Jung, Biological Sciences, Seoul National University, Korea

Scientific Session 06

Bone Marrow Failure syndrome

Date & Time March 30 (Fri), 13:00-14:20 Venue Room B Language English
Speakers

1. Non-Transplant Therapy for Bone Marrow Failure

Danielle Townsley, AstraZeneca Medimmune, USA

2. Role of Microenvironment and Genetics in BM Failure

Myungshin Kim, Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Korea

3. Inherited BM Failure Syndrome

Hoon Kook, Department of Pediatrics, Chonnam National University Medical School, Korea

Scientific Session 07: KOGO-KSH

Cancer Genomics

Date & Time March 30 (Fri), 13:00-14:20 Venue Room C Language English
Speakers

1. Variability in Chromatin Architecture and Associated DNA Repair at Genomic Positions Containing Somatic Mutations

Seon-Young Kim, Gene Editing Research Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Korea

2. Deciphering the Cell-of-Origin Harboring Driver Mutations in Brain Tumors

Jeong-Ho Lee, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Korea

3. Contribution of Germline Variants in Pan-Cancer Development

Youngil Koh, Department of Internal Medicine, Seoul National University Hospital, Korea

4. Developing a Genetic Data based Prognostic Model for Hematologic Cancer

SeungHyun Jung, Cancer Evolution Research Center, College of Medicine, The Catholic University of Korea, Korea

Asian Hematology Network: JSH-KSH Joint Symposium 02

Explore Deep Inside the Asian Hematology Network

Date & Time March 30 (Fri), 14:40-15:40 Venue Room A~B Language English
Speakers

1. AML Prognosis based on Clinical and Genomic Data

Hyeoung-Joon Kim, Department of Internal Medicine, Chonnam National University Medical School, Korea

2. A Novel Mechanism of Cancer Immune Evasion in Human Cancers

Seishi Ogawa, Department of Pathology and Tumor, Kyoto University, Japan

Satellite Symposium 07

ROCHE

Date & Time March 30 (Fri), 14:40-15:20 Venue Room C Language English
Speakers

1. Advancing Value Based Approaches in the Treatment of NHL: Contemporary Strategies and Innovations

Hyeon-seok Eom, National Cancer Center, Korea

KSH-EHA Joint Symposium 02

Aplastic Anemia - Paroxysmal Nocturnal Hemoglobinuria

Date & Time March 30 (Fri), 15:40-17:00 Venue Room A~B Language English
Speakers

1. Diagnosis and Management of AA and Refractory Cytopenia of Childhood

Ayami Yoshimi, University of Freiburg, Germany

2. Frontline Alternative Donor SCT Versus Immunosuppressive Treatment for Children with Severe AA Who Lack Matched Related Donor

Hyoung Jin Kang, Department of Pediatrics, Seoul National University College of Medicine, Korea

3. An Update on the Management of PNH

Anita Hill, Department of Haematology, St. James's University Hospital, UK

4. Clinical Implications of Renal Dysfunction in Patients with PNH

Jin Seok Kim, Department of Internal Medicine, Yonsei University College of Medicine, Korea

Special Report 02

Multiple Myeloma Niche

Date & Time March 30 (Fri), 15:40-17:00 Venue Room C Language English
Speakers

1. Clinical Implications of MRD in Multiple Myeloma

Wee Joo Chng, National University Cancer Institute, Singapore

2. The Ubiquitin-Proteasome Pathway : Friend and Foe in Multiple Myeloma

Robert Orlowski, The University of Texas MD Anderson Cancer Center (MDACC), USA

3. Cellular Immunotherapy in Multiple Myeloma

Je-Jung Lee, Department of Hematology-Oncology, Chonnam National University Medical School, Korea

Satellite Symposium 08

TAKEDA

Date & Time March 30 (Fri), 17:10-17:50 Venue Room C Language English
Speakers

1. Novel Treatment Strategies for Multiple Myeloma: A Focus on Oral Proteasome Inhibitors

Antonio Palumbo, Distinguished Research Fellow Oncology, Takeda Pharmaceuticals International AG, Italy

March 31 (Saturday)

Scientific Session 08

Current Progress in Pediatric Acute Leukemia

Date & Time March 31 (Sat), 09:30-10:50 Venue Room A Language English
Speakers

1. New Developments in the Treatment of Newly Diagnosed and Relapsed ALL

Stephen Hunger, Children's Hospital of Philadelphia, USA

2. Therapy Optimization in Infant ALL

Daisuke Tomizawa, National Center for Child Health and Development, Japan

3. Genomic Landscape and Therapy Optimization of Pediatric Mixed Phenotype Acute Leukemia

Hiroto Inaba, St. Jude Children's Research Hospital, USA

Scientific Session 09

Detetion of Minimal Residual Disease in Hematologic Malignancy

Date & Time March 31 (Sat), 09:30-10:50 Venue Room B Language English
Speakers

1. MRD Detection in Acute Leukemia, CLL and Multiple Myeloma

Alberto Orfao, University of Salamanca (USAL), Spain

2. NGS-based Assessment of Clonality & MRD Determination in ALL

In-Suk Kim, Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Korea

3. [Selected Short Talk I] Development and Preliminary Evaluation of Customized pan-Blood Cancer NGS Panel

Jun Hyung Lee, Department of Laboratory Medicine, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Korea

4. [Selected Short Talk II] Evaluation of Two Commercial Kits for Flow Cytometric MRD Detection in B-ALL

Ari Ahn, Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Korea

Plenary Lecture 03

Development of Precision Medicine Trials

Date & Time March 31 (Sat), 11:10-12:30 Venue Room A~C Language English
Speakers

1. Development of Precision Medicine Trials for ALL

Stephen Hunger, Children's Hospital of Philadelphia, USA

2. Progress in Therapy of Philadelphia Positive ALL

Farhad Ravandi, MD Anderson Cancer Center, USA